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To tackle the problem of insulin resistance in type-2 diabetics, Glenmark launched Lobeglitazone in India for the first time. The medicine helps in making body cells more receptive to insulin.

With this, Glenmark has become the first pharmaceutical company to launch Thiazolidinedione Lobeglitazone drug which works as an insulin sensitiser. The anti‐diabetic medication will be marketed under the brand name LOBG and will be sold for 10 per tablet.

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Glenmark's Lobeglitazone will provide not only improve glycemic(sugar) levels in uncontrolled diabetics, but it will also create a new pathway to treat insulin resistance in India.

Around 40 per cent of diabetics in India suffer from Insulin resistance

“As per the International Diabetes Federation, diabetes affects 74 million adults in India, of which, around 40% of them seem to be insulin‐resistant. As a leading solutions provider in India for the treatment of diabetes, we are proud to introduce LOBG; an innovative and affordable drug, which will help in tackling insulin resistance among adult patients suffering from uncontrolled Type 2 diabetes in the country," said Alok Malik, EVP & Business Head ‐ India Formulations, Glenmark Pharmaceuticals.

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Insulin is a hormone that is produced in the human body by the pancreas to use sugar in the form of energy. There are many causes of type-2 diabetes ranging from low insulin levels, to high insulin resistance of human body organs.

People suffering from type-2 diabetes often face the problem of their organs being unable to use insulin for breaking down sugar to generate energy. This leads to an increase in blood sugar levels causing diabetes.

Glenmark medicine was approved by the Indian drug regulator, Drug Controller General of India, for manufacturing and marketing based on a randomized, double‐blind Phase 3 clinical trial. The trial results indicated a faster and improved glycemic control with Lobeglitazone.

Glenmark's earlier medicines have also contributed to the effective treatment of patients suffering from type-2 diabetes. The company launched the DPP4 inhibitor in India for the first time. It also began manufacturing a fixed dose combination of Teneligliptin + Metformin. The company launched Remogliflozin, a novel SGLT‐2 inhibitor in 2019.

As per the International Diabetes Federation (IDF), as much as 125 million people will be suffering from diabetes by 2045. The alarming situation requires the need to launch more such medicines and lifestyle changes.

 

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Updated: 06 Oct 2022, 11:42 AM IST
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