US stocks opened slightly lower on Thursday led by financial stocks as investors digested the European Central Bank's move to push out its first post-crisis rate hike until at least 2020 and a new round of cheap loans to boost the euro zone economy.

The Dow Jones Industrial Average fell 28.01 points, or 0.11%, at the open to 25,645.45. The S&P 500 opened lower by 4.92 points, or 0.18%, at 2,766.53.

The Nasdaq Composite dropped 22.13 points, or 0.29%, to 7,483.79 at the opening bell.