COVID-19 surge in US: XFG Stratus variant now dominant in 19 states — Symptoms to Watch
COVID-19 cases are rising across the US, driven by the highly contagious XFG “Stratus” variant. Wastewater data shows Stratus now accounts for infections. Hotspots include California, New York, and North Carolina.
As the fall season begins, COVID-19 cases are rising again across the United States, fueled by the highly contagious XFG "Stratus" variant.
According to the US Centers for Disease Control and Prevention (CDC), national COVID-19 viral activity in wastewater is at a “moderate” level. However, 19 states report “high” or “very high” levels, including California, Connecticut, Delaware, Utah, Nevada, and North Carolina. Other states with rising activity include Alabama, Arkansas, Indiana, Louisiana, Massachusetts, Minnesota, Montana, Nebraska, New York, Oregon, Rhode Island, South Dakota, and Washington.
Wastewater data shows that the Stratus variant now accounts for most of US COVID-19 cases, making it the dominant strain nationwide. First detected in the US in March, XFG has rapidly overtaken the previously dominant NB.1.8.1 (“Nimbus”) variant.
About the Stratus Variant (XFG)
The XFG “Stratus” variant is a recombinant hybrid of two Omicron subvariants, LF.7 and LP.8.1.2, giving it a genetic advantage in spreading and evading immunity. While highly transmissible, the variant is not expected to cause more severe illness than previous strains, according to the World Health Organization.
Common symptoms of Stratus
Sore throat
Cough
Congestion or runny nose
Fever or chills
Shortness of breath
Loss of taste or smell
Fatigue, headache, and muscle aches
Nausea, vomiting, or diarrhea
Vaccines and protection
COVID-19 vaccines remain effective at preventing severe illness, complications, and death from the Stratus variant. The FDA has approved updated 2025–2026 COVID-19 vaccines targeting LP.8.1 for high-risk individuals over 65 or with underlying health conditions. Pediatric and obstetric groups also recommend vaccination for children and pregnant or lactating women.
Public health guidance
Health experts urge Americans to continue protective measures as COVID-19 cases rise:
Stay up to date with vaccinations
Test if symptomatic
Isolate when sick
Wear N95 masks in crowded indoor spaces
Maintain social distancing